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What is tenofovir disoproxil fumarate?
Tenofovir disoproxil fumarate (tenofovir DF) is a prescription medicine approved by the U.S. food(FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg). Tenofovir DF is always used in combination with other HIV medicines.
Tenofovir DF belongs to a group of HIV drugs called nucleotide reverse enzyme called reverse transcriptase. By blocking reverse transcriptase, NRTIs prevent HIV from multiplying and can reduce the amount of HIV in the body.inhibitors (NRTIs). NRTIs block an HIV
HIV medicines can’t cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV . If you are taking HIV medicines, including tenofovir DF, don’t cut down on, skip, or stop taking them unless your health care provider tells you to.
Tenofovir DF is also approved by FDA for the treatment of chronicB infection (HBV) in adults and children 2 years of age and older who weigh at least 22 lb (10 kg). For information on the use of tenofovir DF in people with HIV and HBV, please refer to the HBV section of the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents.
How should I take tenofovir disoproxil fumarate?
1. Testing: Prior to initiation of HepBest, test patients for HIV infection. HepBest alone should not be used in patients with HIV infection. Assess serum creatinine, serum phosphorous, estimated creatinine clearance, urine glucose, and urine protein before initiating HepBest and during therapy in all patients as clinically appropriate.
2. Recommended dosage: 25 mg (one tablet) taken orally once daily with food.
3. Renal Impairment: HepBest is not recommended in patients with estimated creatinine clearance below 15 mL per minute
4. Hepatic Impairment: HepBest is not recommended in patients with decompensated (Child-Pugh B or C) hepatic impairment.
HepBest is a generic hepatitis B virus prescription medicine from Mylan, which is one of the biggest pharmaceutical company in India.
Worsening of hepatitis B infection. Your hepatitis B (HBV) infection may become worse (flare-up) if you take Tenofovir and then stop taking it. A “flare-up” is when your HBV infection suddenly returns in a worse way than before.
o Do not run out of Tenofovir. Refill your prescription or talk to your healthcare provider before your Tenofovir is all gone.
o Do not stop taking Tenofovir without first talking to your healthcare provider. o If you stop taking Tenofovir, your healthcare provider will need to check your health often and do blood tests regularly for several months to check your HBV infection. Tell your healthcare provider about any new or unusual symptoms you may have after you stop taking
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